Henoch-Schonlein Purpura -A systemic vasculitis (inflammation of blood vessels)
characterised by deposition of immune complexescontaining the antibody IgA in the
skin and kidney – occurs mainly in children and teenagers – generally occurring more
in boys than girls.
Henoch-Schonlein purpura is a disease that involves purple spots on the skin, joint
pain, gastrointestinal problems, and glomerulonephritis (a type of kidney disorder).
Henoch-Schonlein is caused by an abnormal response of the immune system. It is unclear
why this occurs.
HSP causes skin rash, pain in the abdomen, and joint inflammation (arthritis). The
rash of skin lesions appears in gravity-dependent areas, such as the legs.
The joints most frequently affected with pain and swelling are the ankles and the
knees.
People with HSP can develop fever.
Inflammation of the blood vessels in the kidneys can cause blood and/or protein in
the urine. Serious kidney complications are infrequent but can occur.
