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Clinically, it is very difficult to distinguish Balo’s-Concentric-Sclerosis from Multiple Sclerosis, however MRI scans will show the lesions in Balo’s to be concentric rings of intact myelin and demyelinated zones.

 

Balo's concentric sclerosis is a very rare and acute condition. It is most common in Chinese and Philippino populations.

Attacks of BCS proceed very rapidly over weeks or months, without any remission, in a manner similar to Marburg's MS. Often these result in severe disability or death within months.

More recently, however, an increasing number of cases have been reported where the disease has been self-limiting with some remission.

As with MS relapses, BCS attacks may respond to corticosteroids (steroids)

Symptoms tend to be of a more cognitive nature, such as:

 

 

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Other symptoms may be observed, such as:

BCS lesions are found in the central nervous system white matter of the cerebral hemispheres, cerebellum, brainstem, spinal cord, and optic chiasm.

As well as demyelination, BCS also involves the destruction of the myelin producing cells, the oligodendrocytes.

Currently:

There is not a known cause for Balo disease.

There isn't a cure for Balo disease, but there are treatment options. Always consult your health professional.

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Balo’s Concentric-Sclerosis