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Absorption - Once foodstuffs have been broken down into their constituent parts the essential nutrients are absorbed through the wall of the duodenum and small intestine. Transporting sugars (carbohydrates) and amino acids (protein) into your bloodstream and lipids (fats) into your lymphatic system.

In a healthy person this process works quite efficiently, however, sugars and amino acids require some help, they are not necessarily absorbed unaided.

An energy dependent process known as ‘active transport’ assists the process of absorption, involving carrier molecules transporting  nutrients through the epithelial cells of the gut wall, into the blood stream. Similar to having the right key to fit the right lock, various carriers molecules match themselves to different nutrients, that combination may only pass through certain cells (binding sites), if the combination of nutrients does not match the site it will not be absorbed .

Vitamins and minerals are transported and absorbed in a similar manner, anywhere between the duodenum and the colon. Minerals requiring an acid environment for absorption enter through the wall of the duodenum. Trace elements like zinc are gastric acid free and ‘chelates’ (joins together like two pieces of a jig saw puzzle) with an amino acid before it can be transported across the gut wall.

Fat soluble vitamins are absorbed through the wall of the lower part of the small intestine, whilst water soluble vitamins are are absorbed through the upper part of the small intestine, the exception being vitamin B12, a large molecule that has to combine with a protein, produced in the stomach, known as the intrinsic factor before it is absorbed.

The absorption (uptake) process is complex involving, feedback mechanism’s, electrical signals, and special receptors (binding sites).

Many minerals and trace elements antagonise each other therefore caution is needed when taking supplements, it is quite easy to create imbalances in the body which may compromise your health.

Those with disease / disorder problems very often will experience absorption problems (malabsorption).

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Malabsorption

A state arising from abnormality in absorption of food nutrients across the gastrointestinal (GI) tract.

Impairment can be of single or multiple nutrients depending on the abnormality. This may lead to malnutrition and a variety of anaemia's.

Malabsorption means the failure of the GI tract, usually the small intestine, to absorb one or more substances from the diet. This is generally the result of some defect or damage to the mucosal lining of the small intestine where most nutrient absorption takes place.

 

The most common symptoms of malabsorption:

Over time, one may become deficient in iron, proteins, various vitamins and minerals and this can lead to degrees of malnutrition and a variety of anaemia's.

The most common anaemia's that may occur are:

Vitamin K malabsorption causes the blood to thin out and could result in excess bleeding.

Protein depletion can lead to impaired bone formation and osteoporosis.

Calcium deficiency leads to weakening and demineralisation of the bone, causing a condition called osteomalacia.

Impaired absorption of vitamin A could result in poor vision and night blindness as well as dermatitis.

Malabsorption of protein, fat and carbohydrate leads to loss of calories, generalised malnutrition and diarrhoea.

 

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Absorption